Order Code
2081
Preferred Specimen
Submit 20 mL of random urine. Keep specimen refrigerated.
ContainerType
Urine collection container
Minimum Volume
1 mL
Transport Temperature
Refrigerated
Expected Turnaround Time
1 day
Specimen Stability
2 days room temperature; 6 days refrigerated; 6 months frozen
Methodology
Roche COBAS enzymatic creatininase method, gen. 2. This method has been standardized against ID/MS. Method conforms to nkf recommended creatinine analysis. Note: STAT or regional laboratory testing may use different methodology and/or manufacturer. For more information, see client announcement at http://www.cpllabs.com/egfr_calc
Overview
Creatinine is a byproduct of creatine phosphate metabolism in skeletal muscle and is excreted primarily through the kidneys. In healthy individuals, its production and excretion remain relatively constant.
Urinary creatinine measurement is commonly performed alongside other tests to evaluate kidney function and assist in the diagnosis and monitoring of renal impairment. A random (“spot”) urine creatinine level is frequently used in combination with serum creatinine, serum sodium, and urine sodium to calculate the fractional excretion of sodium (FENa). FENa reflects the proportion of filtered sodium that is excreted in the urine versus reabsorbed by the kidneys.
Clinically, FENa helps differentiate the underlying causes of renal dysfunction, whether prerenal (e.g., hypovolemia), intrinsic renal, or postrenal (e.g., obstruction).
See also: Sodium, Urine, 24-Hour or Random.
Clinical Significance
Aid in evaluation of renal function
Alias
- Creatinine, random urine
- Random urine creatinine
- Urine creatinine, random
Test Setup Days
Monday through Friday PM shift
CPT
82570 LOINC: 2161-8
Reference Range
REFERENCE RANGE FOR RANDOM URINE SAMPLES NOT ESTABLISHED
| UNIT CODE | UNIT CODE NAME | ANALYTE | GENDER | AGE | REFERENCE RANGE | Units of Measure |
|---|---|---|---|---|---|---|
| 2081 | RDUCREA | CRCON | NOT SPECIFIED | ALL | NOT ESTAB | MG/DL |
| 2081 | RDUCREA | CRCON | MALE | ALL | NOT ESTAB | MG/DL |
| 2081 | RDUCREA | CRCON | FEMALE | ALL | NOT ESTAB | MG/DL |